
PMS/PMDD-associated EF deficits may be addressed from a neuropsychological perspective in two ways: (a) mild-to-moderate impairments evidenced by neuropsychological testing are suspected due to corresponding brain anomalies (e.g., frontal lobe dysfunction to regulate limbic responses) (b) symptoms of the disorder may be understood as affective and behavioral manifestations of cognitive deficits (e.g., rumination of negative thoughts as cognitive inflexibility and deficits in updating of working memory, impulsivity as poor inhibition of response, anxiety as excessive attentional bias toward threat).

These symptoms manifest themselves during the luteal phase of the menstrual cycle, peak two days before menstruation begins, and diminish within the first days of menstruation (Īs with other depressive disorders, PMS/PMDD may be neuropsychologically understood as impairments of executive functions (EF), since these are related to regulation of complex behavior and cognition and thus underly or are closely related to the dynamics of most psychopathologies ( Premenstrual dysphoric disorder (PMDD) is considered a severe form of premenstrual syndrome (PMS), characterized by physical (e.g., breast fullness, weight gain), affective (e.g., depression, anxiety), cognitive (e.g., decreased concentration), and behavioral (e.g., sleep disturbances and impulsivity), all of them symptoms that produce a significant impairment in the daily functioning of women.
